After injecting prostate cancer cells into the left tibia of Balb/c nude mice, Thulin’s team performed bone tumor development status assays using peripheral quantitative computed tomography (CT) and microCT to investigate the effect of signal transducer and activator of transcription 3 (STAT3) inhibitors on STAT3-regulated prostate cancer bone metastasis. This evidence concerns the gene STAT3 and prostate carcinoma.