Therefore, we can speculate that acupuncture treatment can promote the expression of BDNF protein in the cerebral ischemic region of stroke patients, thus promoting the survival of brain cells and the reconstruction of neuronal circuits to increase the number of dendritic spines in hippocampal neurons, promoting synaptic remodeling, and enhance synaptic plasticity to promote the recovery of language function. The gene discussed is BDNF; the disease is Stroke.