The high expression of TMEM131L was enriched in cancer-related molecular signaling pathways, long-term depression, insulin signaling pathway, melanin production (Figure 15C), and the low expression of TMEM131L was enriched in the PPAR signaling pathway, systemic lupus erythematosus, and oxidative phosphorylation route (Figure 15G). This evidence concerns the gene TMEM131L and systemic lupus erythematosus.