Relative to the patients in the depression group after ICH, those in the non-depression group presented higher baseline NIHISS1 scores (p < 0.001), higher NIHISS2 scores (p < 0.001), higher WBC (p < 0.001), higher CRP (p < 0.001), higher RDW (p < 0.001), higher mRS scores (p < 0.001), and lower BI scores (p < 0.001). The gene discussed is CRP; the disease is major depressive disorder.