In Kuwaiti T1DM patients who carried the other high-risk HLA-DQ2/DQ8 genotype, 39/56 (70%) had the homozygous CC genotype and 87% co-inherited at least one variant “C” allele of the IL4 gene polymorphism along with the high-risk HLA-DQ2/DQ8 genotype (Figure 3). The gene discussed is IL4; the disease is type 1 diabetes mellitus.