Concerning genetic cases, several studies reported BG alterations in ALS patients carrying C9orf72 mutation (C9ALS) (Bede et al., 2013; Westeneng et al., 2016; De Vocht et al., 2020; Ahmed et al., 2021; Spinelli et al., 2021). This evidence concerns the gene C9orf72 and amyotrophic lateral sclerosis.