Decreasing the plasma levels of AST, ALT, TG, TCHO, LDL/VLDL.Decreasing the wet kidney/body weight ratio and reducing plasma CREA levels.Increasing the plasma HDL, reducing glomerular basement membrane thickening and plasma CREA levels and improving the pathological changes of nephropathy and cardiac hypertrophy.Exhibiting potential anti-hyperglycemic effects and protecting against diabetes-related complications. The gene discussed is GPT; the disease is diabetes mellitus.