However, among sera of HIV-infected participants, high CD4 counts, virological control (>40copies/mL) and ART duration, seemed individually associated to the presence of SARS-CoV-2 antibodies; suggesting that people with a highly compromised immune system, an uncontrolled viral replication and/or the absence of an effective ART-regimen stand a high risk of not controlling SARS-CoV-2 replication or developing severe symptoms of COVID-19 (13). Here, CD4 is linked to COVID-19.