CD4 and neoplasm: Higher colocalization of tumor cells (CK) and some biomarkers was significantly correlated with better survival, such as CD3+ (DFS, P=0.0580; OS, P=0.0465), CD4+ (DFS, P=0.0031; OS, P=0.0037), and CD8+ (DFS, P=0.0444; OS, P=0.0152, Table 4; Figure 3D).