Significantly smaller tumors were observed in mice grafted with either ESRP1 or ESRP2, compared to scrambled-grafted mice, while the reduction in tumor was even more pronounced in mice grafted with T24 cells transfected with combined ESRP1/2, shown by quantification (Figure 5A), and by representative images (Figure 5B). This evidence concerns the gene ESRP2 and neoplasm.