NANOG and posterior cortical atrophy: PCa cells can also evade NK cell-mediated death due to high NANOG expression (a pluripotent-related transcription factor), repressing ICAM-1, a cell adhesion molecule that is necessary for the β2 integrin lymphocyte function associated antigen 1 (LFA-1)-dependent early stimulatory signal for NK cell cytotoxicity, whose low expression is correlated with a high recurrence rate in PCa patients (71, 72).