Our findings clearly confirm the prominent role of variants in LRRK2 and GBA1 on increased PD risk, in particular: LRRK2 p.R1441H, p.L1795F and p.G2019S; and GBA1 p.S146L, p.D179H, p.R296Q, p.E365K, p.T408M, p.N409S and p.R502C. This evidence concerns the gene LRRK2 and Parkinson disease.