SREBF1 and cancer: Figures 2C+2D shows that the expressions of SREBF1 and STARD4 were significantly higher in mid to late-stage than in early-stage tumors. During cancer progression, the expressions of SREBF1 and STARD4 were significantly higher in the lymph node metastatic stage than in normal tissues (Figs. 2E+2F). Analyses of SREBF1 and STARD4 expressions with tumor grade indicated that their expressions increased significantly with increasing tumor grade (Figs. 2G+2H).