On the other hand, the reference genotype “GG,” didn't show any significant difference in the median VEGF-A levels amongst both T2DM (128.0 (110.0–143.0), P = 0.48) and DFU (103.2 (99.4–108.8), P = 0.05), as compared with healthy controls participants (114.6 (107.8–135.3)). Here, VEGFA is linked to type 2 diabetes mellitus.