CD8A and nonpapillary renal cell carcinoma: According to the score comparisons of immune cells and immune function, we observed that high-risk patients possessed higher scores in helper T cells 2 (Th2 cells), CD8+ T cells, follicular helper T cells (Tfh), helper T cells 1 (Th1 cells), and T cell co-stimulation, suggesting a potential therapeutic agent in ccRCC with nelarabine.