In addition, this studyrevealed that PSMA3-AS1 affected FLT3-ITD+ AML bytargeting expression of miR-20a-5p, and miR-20a-5p further modulated expressionof ATG16L1, an mRNA that down-regulated in AML, to affect disease advancement. The gene discussed is FLT3; the disease is acute myeloid leukemia.