The panel strongly agreed on biomarkers associated with T2 inflammation that are useful for the follow-up of patients with severe asthma and CRSwNP treated with biologics, including peripheral blood and tissue eosinophil count (M: 8), and FeNO (M: 8), whereas controversy was observed for serum total IgE (M: 7.5) and specific IgE (M: 5) (Table 3). The gene discussed is IGHE; the disease is asthma.