The cGAS‐STING signaling pathway has emerged as a key mediator of inflammation in the setting of infection, cellular stress, and tissue damage.[41] STING activation can trigger cell death in various ways, such as pro‐apoptotic and pro‐necroptotic molecules, autophagy and lysosome‐dependent cell death.[42] However, the function of the cGAS/STING signaling pathway in skeletal muscle disease remains unclear. This evidence concerns the gene STING1 and infection.