In Imo‐induced muscle atrophy, circTmeff1 knockdown enhanced muscle mass, reduced expression of Atrogin‐1 and MuRF‐1, increased CSA of myofibers, and reactivated AKT/FOXO3A/mTOR signaling pathway in this muscle atrophy model (Figure S9, Supporting Information). The gene discussed is MTOR; the disease is Atrophy.