Antagonistic relationships between miR-218 and EGFR have also been demonstrated in glioblastoma (Mathew et al. 2015) and, indirectly, in osteosarcoma (Lin et al. 2020) and esophageal squamous cell carcinoma (Qu et al. 2020). This evidence concerns the gene EGFR and esophageal squamous cell carcinoma.