BEST1 and head and neck squamous cell carcinoma: We found that BEST1 was mainly expressed on monocytes (CD14+) and tumor‐associated macrophages (TAMs) (CD68+) in the TME of HNSCC patients (Figure S2a, Supporting Information), and the positive ratio of BEST1 expression in cancer is significantly elevated than that in adjacent normal tissue (Figure 2a,b).