For this reason, we conducted a β-catenin-immunohistochemical analysis of the majority of the dysplasia cases from mice exposed to DSS, which were available in serial sections of H &E specimens, i.e., five dysplasias from male Polk+/+ mice, 12 from male Polk−/− mice, and seven from female Polk−/− mice. The gene discussed is POLK; the disease is dysplasia.