RV infection at a multiplicity of infection (MOI) 0.1, but not UV-inactivated RV (UV-RV), induced secretion of mature IL-1β 24 h after infection (Fig. 2a, b, Supplementary Fig. 3b, c), which was significantly increased in patients with asthma (Fig. 2b). The gene discussed is IL1B; the disease is asthma.