However, only in asthma, complementary with all our previous data, HDM simultaneously increased the activation status and release of proinflammatory and pro-remodeling proteins, such as IL-1α, signaling lymphocytic activation molecule family member 1 (SLAMF1)63, cluster of differentiation (CD) 4064,65 and TRANCE (RANKL)66,67 (Fig. 5b, Supplementary Table 5). Here, IL1A is linked to asthma.