SNCA and movement disorder: Notably, elimination of microglia attenuated the movement disorder in the Cntnap4+/− + AAV-hα-Syn mice in the OFT and grasping test (Fig. 5K–M), improved nigrostriatal DA neuronal death (Fig. 5N–P), and slightly decreased the endogenous α-synuclein level (Fig. 5Q–S).