Significantly, MGMT is associated with a variety of tumors, such as glioma and glioblastoma [34,35], esophageal adenocarcinoma [36], liver cancer [37], and thyroid cancer [38], etc. In glioma, low DDR scores are associated with MGMT methylated status [10]. The gene discussed is MGMT; the disease is esophageal adenocarcinoma.