Further analysis found patients with high HOOK1 mRNA expression exhibited a lower risk of recurrence (Figure 1E) and negatively correlated with tumor grade and stage (T stage, p < 0.0001; N stage, p = 0.036; non‐metastasis/metastasis, p < 0.0001; TNM stage, p < 0.0001; Clinical stage, p < 0.0001; Histological grade stage, p < 0.0001) (Figure 1F–H). This evidence concerns the gene HOOK1 and neoplasm.