Based on this analysis, we found a significant correlation between the level of macrophages and level of activated HPCs (p = 6.24e‐03, r = 0.37), TNFSF12 expression and level of macrophage (p = 2.51e‐03, r = 0.41), ID1 expression and the level of HPCs activation (p = 6.22e‐04, r = 0.46) in HCC adjacent non‐tumor tissues (Figure 7N). The gene discussed is ID1; the disease is hepatocellular carcinoma.