Table 5 shows that the preoperative and 6 months mean difference HRQoL scores were similar among patients who were in NYHA class I-II vs. III-IV, with normal vs. low preoperative LVEF, with vs. without stroke, hypertensives vs. non-hypertensives, with vs. without pulmonary hypertension, with severe vs. moderate mitral stenosis, with elevated vs. normal CRP, and those who underwent mitral valve replacement vs. double valve. This evidence concerns the gene CRP and pulmonary arterial hypertension.