CCL2 and neoplasm: Regarding inflammation, mRNA expression of Ccl2 (macrophage chemotaxis), Cd68 (tumor associated macrophages, TAMS), Cd163 (M2 TAMs) and Foxp3 (regulatory T cells, Tregs) markers was greatly induced upon LLC challenge in Tert+/+ mice, while this increment was lower and specifically unaltered in the case of Cd163 and Foxp3, in G3 Tert−/− mice (Fig. 3G–J).