CCL2 and neoplasm: On the other hand, mRNA expression of Ccl2 (macrophage chemotaxis marker), Cd68 (tumor associated macrophages, TAMs), Cd163 (M2 TAMs) and Foxp3 (regulatory T cells, Tregs) markers was greatly increased in LLC control mice, while this increment was less pronounced in 6-thio-dG-treated mice (Fig. 7H–K).