It should be noted that UBTF-TD AML were associated with the M6 morphology subtype [34] according to the FAB classification (especially in cases without FLT3-ITD or low ratio) and the diagnosis of AML could thus be made by counting the proportion of BM blasts among the non-erythroid cells according to the FAB criteria [21]. This evidence concerns the gene FLT3 and acute myeloid leukemia.