MAP3K20 and ependymoma: By differential gene expression analysis against other ependymoma tumors, we find that the mitogen-activated protein kinase 20 (MAP3K20) and integrin α6 (ITGA6), the latter encoding the receptor of the extracellular matrix protein laminin, which are both embedded in the chromatin cluster, are transcriptionally upregulated in PFA ependymomas (adj.