IL6 and depressive symptom measurement: This acute IL-6 response was shown to moderate the effect of treatment, such that, in the study sample as a whole, larger immediate IL-6 responses to treatment (WBH and sham groups combined) were associated with reduced HDRS depression scores over the 6-week follow-up period, with this effect being numerically maximal at post-treatment week 2 when examined by simple correlations.