Within IN-axonogenesis, APOEε4 carriers had upregulation of genes PRNP and GPX4 related to “Ferroptosis” (Benjamini–Hochberg p = 1.11 × 10−2, Supplementary Dataset 21g) a pathology often found in AD samples and mouse models65–67. The gene discussed is PRNP; the disease is Alzheimer disease.