Overlapping genes between the target genes of active compounds and liver fibrosis-related genes, including PTGS2, GABRA1, PTGS1, HSP90AB1, PGR, CHRM1, PRSS1, CHRM2, CASP3, and DPP4, may play an important role in the treatment of liver fibrosis. The gene discussed is CHRM2; the disease is Hepatic fibrosis.