TP53 and inborn error of immunity: Under the filter condition normalized enrichment score (NES) >1, Nominal (Nom) P-value<0.05, and false discovery rate (FDR) q-value<0.25, we found that the main enrichment pathways of cluster 2 were ‘cytokine–cytokine receptor interaction’, ‘nucleotide excision repair’, ‘antigen processing and presentation’, ‘cell cycle’, ‘primary immunodeficiency’, and ‘p53 signaling pathway’ (Supplementary Figure S2A).