MEIG1 and male infertility: Disruption of either Meig1 or Pacrg in the male germ cells resulted in a similar phenotype of impaired spermiogenesis and male infertility (Zhang et al., 2009; Li et al., 2015; West et al., 2003; Bennett et al., 1971; Lockhart et al., 2004; Lorenzetti et al., 2004; Taylor et al., 2007).