CD8A and neoplasm: In addition, the combination therapy promoted the repolarization of classical M1 macrophages into cytotoxic FTH1high M1 macrophages, but not M2 macrophages, and also activated macrophages and neutrophils to interact with and recruit DCs, which presented more tumor‐associated antigens (TAAs) to cytotoxic CD8 T+ cells to enhance tumor cell killing.