MKI67 and neoplasm: Western blot analysis of pT389‐S6K and immunohistochemistry of p‐S6 demonstrated that knock in of FLCN‐SD led to mTORC1 activation in tumors (Figure 6F,G), and immunohistochemistry of Ki67 showed that FLCN‐SD regulated tumor cell proliferation in an mTORC1‐dependent manner (Figure 6H).