PRMT6 and male infertility: Only one in three cases of azoospermia can be explained by genetic defects, such as abnormalities and deletion of the azoospermia‐factor (AZF) region in the Y chromosome, whereas more than 70% of the cases are idiopathic NOA (iNOA).[4, 5, 6, 7] In addition to genetic defects, infectious and inflammatory conditions in the reproductive system contribute to male infertility.[8, 9, 10] Genome‐wide association studies of idiopathic male infertility have revealed a series of NOA susceptibility loci, including PEX10, PRMT6, and SIRPA.