As aforementioned, we evaluated the expression of CAPRIN-1 on the membrane surface in numerous cancer cells and found that some cells such as HEC-1-A (uterine), SK-MEL-5 (melanoma), and Malme-3M (melanoma) contain subpopulations with varying expression levels for CAPRIN-1 (Fig. 5A). This evidence concerns the gene CAPRIN1 and melanoma.