ADRs: adverse drug reactions; DRPs: drug-related problems; HCQ: hydroxychloroquine; VAN: vancomycin; TZP: tazobactam; MEM: meropenem; ADEs: adverse drug events; HER2: human epidermal growth factor receptor-2; TNF: tumor necrosis factor; TEN: toxic epidermal necrolysis; SJS: Stevens-Johnson syndrome. This evidence concerns the gene TNF and Stevens-Johnson syndrome.