Age: Median age 47, Sex: 41.9% female patients; Co-morbidities: COPD, Diabetes, Hypertension, Coronary Heart disease, Cerebrovascular disease, Hepatitis B infection, Cancer, Chronic Renal Disease, Immunodeficiency Raised AST >40 U/L: 22.2%, Raised ALT >40 U/L: 21.3%, Raised Total Bilirubin >17.1 μmol/L: 10.5% The gene discussed is GPT; the disease is immunodeficiency disease.