Likewise, in the validation I cohort, IFNAR was ordered first among cancer hallmarks (Figure 2H, HR = 0.640, p = 0.006) (Supplementary Table S3), high IFNAR-related score was linked to better OS (Figure 2I, p = 0.041), IFNAR was significantly upregulated in responders (Figure 2J; Supplementary Table S4). This evidence concerns the gene IFNAR1 and cancer.