CHRNA5 and lung carcinoma: A GWAS study conducted by Zanetti et al. (2016) also discovered two novel loci associations with lung cancer susceptibility in African Americans, including: rs2036527 (CHRNA5 gene in chromosome 15q25.1) and rs2853677 (TERT in chromosome 5p15.33) that was specifically associated with susceptibility for LUAD histology.