PIK3CA and non-small cell lung carcinoma: KRAS mutations were the most common somatic mutations found in NSCLC, followed by EGFR. Moreover, mutations in KRAS, EGFR, BRAF, TP53, and STK11 were frequently identified in LUAD patients, while PIK3CA, and TP53 mutations were commonly found in SCC patients (Campbell et al., 2016).