Previous bioinformatics analysis has demonstrated that COL5A2, COL10A1, and COL11A1 may be used as a diagnostic or prognostic biomarker for tumors such as gastric cancer (Niu et al., 2022), breast carcinoma (Giussani et al., 2018), and non-small-cell lung cancer (Andriani et al., 2018). Here, COL5A2 is linked to non-small cell lung carcinoma.