Hypercholesterolemia not only induces oxidative stress but also contributes to inflammation, as the oxidative stress resulting from dyslipidemia triggers an imbalance between pro-inflammatory and anti-inflammatory mediators by increasing the expression of numerous cytokines, including IL-1β, IL-6, TNF-α, and IL-10 (31). The gene discussed is IL1B; the disease is Hypercholesterolemia.