(2013) identified several miRNAs, among which miR-498 (35), regulating the human epidermal growth factor receptor 2 (ErbB2/HER2) pathway which is one of the driver pathway of BC, showing HER2 overexpression with the constitutive activation of its receptor and leading to a more aggressive form of the disease with the promotion of the metastatic process (35). Here, ERBB2 is linked to breast cancer.