FOXD3-AS1 is a significant high-risk factor for poor prognosis of GBM and LGG in the historical type of astrocytoma and glioblastoma [HR = 2.65 (1.96–3.58), p < 0.001] and oligoastrocytoma and oligodendroglioma [R = 2.08 (1.30–3.33), p = 0.002] (Figures 8G,H). This evidence concerns the gene FOXD3 and glioblastoma.