CAMK2G and hydrops fetalis: This study has shown a transcriptomic remodelling of the protein kinase A, CaMKII, p38-MAP kinase, Hippo, WNT, JAK-STAT and Notch signalling pathways as well as the protein phosphatase interactome in the AV node in HF; it has also shown evidence of an immune response; each of these has been shown in other studies to be involved in cardiac pathological remodelling in disease.