↓ APTT and PT↑ FVII:C, ↓ fibrinogen, ↑ AT, ↑ plasminogen, ↓ t-PA, ↓ PAI, ↓ TAT complex, ↓ d-dimers↓ thrombocytopenia. The gene discussed is SERPINE1; the disease is Thrombocytopenia.