Our findings showed that the levels of NF-κB and Bcl-2 were higher, while the Bax level was lower in the control group than in the bacteria and supernatant groups (Figures 6A, B), which indicated that both CB culture and supernatant promote the pro-apoptosis gene expression and inhibit the anti-apoptosis gene expression, thus inhibiting the development and progression of CRC. The gene discussed is NFKB1; the disease is colorectal carcinoma.